"We were looking for a way to inhibit a protein involved in cell division, the Plk1 protein, when and where we wanted, to better understand its function in the development of an organism." ...
Onvansertib targets the PLK1 isoform only (not PLK2 or PLK3), is ... to abrogate several DNA repair pathways and trigger a robust immune response by activating the innate immune response through ...