The exact molecular functions of Polo-like kinase 1 (PLK1) in mitotic prophase are not fully understood. This study shows that PLK1 inhibition delays activation of CDK1-cyclin B and halts cells for ...
integrating Aurora-B and PLK1 signalling), and the possibility that there are multiple CPC subcomplexes that specialize to control particular mitotic functions. The score for the elaborate and ...
Cell cycle events are controlled tightly by several kinase families including CDKs, Plks, and Aurora kinases. What is interesting about these kinases is that they don't always act alone.
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