Only fused plasmids can propagate because unfused donor ... coexpression of currently up to five genes of interest in transfected cells. In addition, MultiLabel enables the generation of stable ...

Ultimately, this means that transfected SV40-containing plasmids can undergo episomal replication, which enhances the amount of recombinant protein/retroviral production.

Bacterial cells often possess molecules of closed, circular DNA, otherwise known as ‘plasmids’. They can also be present at much lower frequencies in certain eukaryotic cell types, such as yeast.

Indeed, the current high demand for plasmids can require booking manufacturing months in advance. Plus, insufficient supplies of pDNA cause expensive regulatory delays in therapeutic programs.

New research from the University of Sheffield has found that bacterial plasmids readily pick up new genes and spread them to new species – something which is an increasing concern for transfer ...

Often found in bacteria, plasmids can carry genes that are useful for survival and can be engineered in the lab to introduce new genes into cells. Scientists use them as tools to study gene ...

A team of Portuguese scientists has reduced the size of helper plasmids for recombinant adeno-associated viral (rAAV) production. The team, from Instituto de Biologia Experimental e Tecnológica ...