A recently developed medication encourages people with cocaine use disorder to reduce their intake of the stimulant – a step ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

We propose that there are existing treatments for the alleviation of negative symptoms, which may provide a novel treatment for patients with comorbid schizophrenia and cocaine abuse.

Prolonged cocaine use can result in severe physical, psychological ... These participants were not seeking treatment for their disorder and were otherwise medically healthy.

For 7 months, efforts were made to treat Halsted’s cocaine addiction with morphine ... due to the enormous mental and physical strain. In 1922, Halsted, who as a young surgeon had saved his ...