Phagocytes may engulf both apoptotic and viable cells via calreticulin on the surface of the target cell, through its interaction with the phagocyte receptor, LRP. In reality, however, only ...

Keywords immune system, lymphocytes, antibodies, phagocytes, antigens, T-cells, infections, medical intervention, immunology, health Email us at [email protected] if you have questions about the ...

A second phase 1 trial plans to evaluate CER-1236, a novel chimeric antigen receptor therapy, for solid tumors.

Efferocytosis is performed upon recognition of “eat-me” signals present in the outer membrane of apoptotic cells. Tissue-resident macrophages posses a wide variety of phagocytic receptors that vary ...

The firm previously said it will test the CER T-cell therapy CER-1236 in blood cancers after receiving FDA manufacturing clearance.

The researchers also discovered that when these cells, called macrophages, eat live bacteria it triggers an inflammation ...

apoptotic cell clearance or ‘efferocytosis’. Efferocytosis is essential for normal development and tissue homeostasis, but also pathogen defense and anti-tumor immunity. A single phagocyte typically ...

Company reports acceptance of an abstract at the 2025 American Society of Clinical Oncology (ASCO) conference; Continues to be on track to dose ...

identified cells that could engulf and destroy foreign pathogens, known as phagocytic cells. This discovery became the basis for immunology. 3 What the Greeks and Metchnikoff observed, and what ...