Restriction enzymes are one of the most important tools ... Human had shown that various phages were host specific, with each phage surviving and flourishing only in one host bacterial strain ...

Here, the authors structurally and biochemically characterize a new anti-phage TA system, ShosTA. The lysosomal enzyme beta-glucocerebrosidase is a key player and promising therapeutic target in ...

To fend off phage attacks, bacteria have evolved their own defense tools, including the most common restriction-modification (R-M) and CRISPR-Cas systems. In addition, bacteria encode a collection ...

Bacteriophages — viruses that infect bacteria — are locked in a constant arms race with their microbial hosts. A family of phages known as jumbo phages have evolved a remarkable strategy of ...