Angiopoietin/Tie (Ang/Tie) signalling similarly controls the association of EC and pericytes 8. Yet, its molecular mechanism-of-action is much less well understood. Tie2 expressed by EC is ...

The loss of pericytes corresponds to the reduced production of Tie2, an essential protein for vascular stabilization, in par with the activation of FOXO1, which is responsible for the production ...

The blood–retinal barrier (BRB) consists of tightly interconnected capillary endothelial cells covered with pericytes and glia ... blocking Ang2 or activating Tie2 greatly attenuates BRB ...

The antibody—called ABTAA, or angiopoietin-2 (Ang2)-binding and Tie2-activating antibody ... by endothelial cells and other cells called pericytes, the endothelial junctions are broken ...

Pericytes are cells that wrap around the endothelial cells that line the capillaries and venules throughout the body. They are located in the basement membrane which allows them to communicate ...

A new study, published in the journal Neuron, reveals the crucial role of vascular system cells -- known as pericytes -- in the formation of long-term memories of life events -- memories that are ...

Capitalizing on the flexibility of tiny cells inside the body's smallest blood vessels may be a powerful spinal cord repair strategy, new research suggests. In mouse experiments, scientists ...

Cells in the brain called pericytes that have not been high on the list of targets for treating diseases like Alzheimer's may play a more crucial role in the development of neurodegenerative ...

In addition to these jobs, pericytes also work with neurons to form and store long-term memories, according to a study published Monday (Oct. 2) in the journal Neuron. "We now have a firmer ...

So they are running this small study to collect blood samples from women having bevacizumab. The main aims of this study are to: confirm that the Tie2 blood test works in women having bevacizumab for ...

Aging causes a reduction of the protein Tie2, a risk factor for increased intraocular pressure and glaucoma. In this experiment, one eye of mice lacking Ang1 and Ang2 was injected with the ...

The loss of pericytes corresponds to the reduced production of Tie2, an essential protein for vascular stabilization, in par with the activation of FOXO1, which is responsible for the production ...