“The human protein known as PCNA [proliferating ... is found normally, to the cytoplasm, a cellular region containing organelles responsible for important cell functions. According to the ...

The proliferating cell nuclear antigen (PCNA) is an essential protein for DNA replication and damage repair. How its function is controlled remains an important question. Here, we show that the ...

image: Cell culture trial shows interaction between cellular protein PCNA and ... to the cytoplasm, a cellular region containing organelles responsible for important cell functions.

Figure 1: Cdt1 binds to PCNA via a conserved PIP box. Figure 2: Replication of M13 ssDNA induces PCNA-dependent Cdt1 destruction. Figure 3: PCNA-dependent Cdt1 destruction in LSS limits DNA ...

Human protein PCNA (red) migrates from cell nucleus (blue) to cytoplasm in the presence of protein M (green) Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases ...

such as use of compounds to inhibit migration of proteins from the nucleus to the cytoplasm. In cells treated with both a specific compound for PCNA and another that inhibits migration of ...