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The new molecules target a metabolic pathway ... Edition. Bacterial cells differ fundamentally in their structure from animal and human cells. For example, bacteria have a rigid cell wall, whereas ...

Back in the 1940s, Efraim Racker had just figured out the mechanism by which cells glean a little energy from the breakdown of glucose in the absence of oxygen, a pathway known as glycolysis.

Once the cell envelope loses its shape, all of the bacteria eventually burst open and die, Goley says. "We established a model for how either depleting OPGs or activating the signaling pathway ...