Despite improvements in neuroblastoma treatment, survival figures lag behind those of many other childhood malignancies. New treatments, and better use of existing treatments, are essential to reduce ...

Pathway-specific Expression Analyses Indicate Tumor Behavior and May Serve as a Guide to Targeted Treatment The overall genomic alteration pattern reflects the genetic damage of neuroblastoma ...

A groundbreaking study in Nature Medicine reveals that GD2 CAR-T cell therapy can lead to long-term remission in children ...

Five-year-old Annabel Ashmore, from Gateshead, needs to start a two-year treatment by November to reduce the risk of her stage four neuroblastoma ... there is a potential pathway there and every ...

Neuroblastoma (NB), the most prevalent extracranial ... and were characterized by an active cell cycle and DNA repair ...

A small but in-depth study of allogeneic CAR T cell therapy in patients with high-risk neuroblastoma shows feasibility and potential efficacy, and mechanistic insights reveal pathways to improved ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.