Another active area of research in the laboratory focuses on unraveling the mechanisms behind maladaptive, or pathological, and adaptive, or physiological, cardiac hypertrophy. In response to certain ...

Pathologic left ventricular hypertrophy can occur in the setting of hypertrophic obstructive cardiomyopathy even in the absence of increased afterload. The ECG findings of left ventricular ...

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components ...

Aim Differentiating physiological cardiac hypertrophy from pathology is challenging when the athlete presents with extreme anthropometry. While upper normal limits exist for maximal left ventricular ...

Notably, cardiac hypertrophy is also a leading risk factor for the development of heart failure. However, in this pathological setting, cardiac remodeling is not reversible. My project is focused on ...

Background: Atrial function is an integral part of cardiac function that is often neglected. The presence of left ventricule hypertrophy (LVH ... is present in patients with either physiological or ...

We aim to find ways to promote cardiomyocyte renewal after a myocardial infarction and strategies to inhibit pathological cardiac remodelling: hypertrophy (thickening) and fibrosis (stiffening). We ...

this contributes to the pathology of the disease by, among other actions, increasing the release of aldosterone. Aldosterone has been shown to cause coronary inflammation, cardiac hypertrophy ...