Hepatocellular carcinoma (HCC) is one of the deadliest ... HCC research has increasingly focused on understanding its pathogenesis and developing treatments.The Wnt signaling pathway, a complex ...

The classical two-hit hypothesis from which the current complex "multiparallel" theory has been developed to understand the pathogenesis of NASH relies on an initial hit of hepatic steatosis ...

In early-stage HCC patients (BCLC 0 and A), CP mRNA was elevated in 67.9% of cases, outperforming AFP, which detected only 46 ...

Hepatocellular carcinoma (HCC), the most common form of liver cancer, continues to pose a significant global health challenge ...

Systemic therapy represents the standard of care treatment for patients with advanced hepatocellular carcinoma (HCC). Given ...

and hepatocellular carcinoma. A clear understanding of cellular processes in MASH pathogenesis is essential for developing ...

There is therefore an urgent need for the development and testing of novel agents targeting pathways thought to be involved in the pathogenesis ... cell carcinoma and unresectable hepatocellular ...

However, MASLD is a heterogeneous disease regarding its pathophysiology and clinical ... cirrhosis and hepatocellular ...

The FDA approved nivolumab and ipilimumab for unresectable or metastatic hepatocellular carcinoma, a prevalent and deadly liver cancer in the U.S. CHECKMATE-9DW trial results showed improved ...