Recently, second-generation antipsychotics (SGAs), olanzapine plus fluoxetine, quetiapine extended release and aripiprazole have clearly demonstrated efficacy in the treatment of MDD patients ...

The mean change in weight was highest with OFC (+4.4 kg) and comparable with olanzapine (+4.6 kg), while it was the least with fluoxetine (-0.2 kg). The proportion of patients gaining weight ≥ 7 ...