Researchers have found that deficiency of an antioxidant response ... Nuclear erythroid-2 like factor-2 (Nrf2) is a key regulatory protein in the signaling pathway that triggers the body’s ...

Esophageal cancer remains one of the world's deadliest cancers, ranking 7th in incidence and 6th in cancer-related deaths ...

In mice with the tweaked genes, high levels of Nrf2 and antioxidants actually encourage ... Recognizing this newfound pathway as a “potent promoter of metastasis” could help doctors develop ...

In a study published in the journal Free Radical Biology and Medicine, researchers from the University of Utah and other institutions found that aged mice lacking the antioxidant protein Nrf2 that ...

"With our latest study, we show how the NRF2 pathway reprograms glucose metabolism ... by affecting metabolic pathways as well as decrease antioxidants and detoxification genes to intervene ...

Antioxidants are commonly used to treat ... Cell experiments revealed that the drugs activated the NRF2 signaling pathway, which triggered the expression of metastasis-promoting proteins.

Research finds alpinetin, a natural compound, can protect cartilage from iron overload damage by boosting antioxidant ...

Excessive sequestration of KEAP1 into phase-separated p62 bodies under conditions of impaired autophagy drives persistent ...

Analysis of fluid around those astrocytes revealed high levels of another antioxidant called glutathione, which is part of a pathway controlled by a protein called Nrf2, defects in which have been ...