The Notch genes encode a conserved family of receptors that influence developmental fate in many species. Prior studies have indicated that Notch-1 and Notch-2 signaling influence the development ...

This may have important consequences for tumorigenesis but the exact role of Notch genes in cancer development is not known. In September 1 Genes and Development Claudio Talora and colleagues from ...

Under these conditions, Hes-1 expression was mediated, at least in part, by a Notch-independent mechanism involving c-jun N-terminal protein kinase (JNK) signaling. This is the first report ...

Expression levels of the Notch1 ... ZhuGe Q, Zhong M, Zheng W, et al. Notch-1 signalling is activated in brain arteriovenous malformations in humans. Brain 2009; 132(Pt 12): 3231–3241. 12. Tu J, Li Y ...

ACROBiosystems provides a wide range of Notch 1/2/3/4 protein and DLL3 products that are expressed with the HEK293 expression platform. Many labels are available, with validated applications such ...