and neoplasia (Lewis lung cancer model); that the effect of nicotine on vascular structure is associated with functional changes in tissue blood flow and tissue growth; and that the proangiogenic ...

The project uses various approaches to determine the molecular, cellular, physiological and behavioral consequences of the Chrna5 D398N polymorphism. Identify genes that influence nicotine consumption ...

The structure of the ion channel in its potentially open and closed conformations and the site for channel blockers are known from studies on bacterial homologues. Structural and molecular ...