Nicotine inhalation system 10mg (4mg delivered); per cartridge ... then reduce gradually over 12 more weeks. Inhaler: peak plasma concentrations of 49ng/mL reached within 15 minutes.

Since each inhaler cartridge can deliver up to 4 mg of nicotine, the total daily nicotine dose for the typical FDNY firefighter could have been 63 mg of nicotine per day, a threefold- to fourfold ...