To verify that the PNA–NLS binds to the cognate sequence in the oligonucleotide ... an SV40 NLS peptide can work as a nuclear targeting signal when hybridized to a fluorescence-labeled ...

ErbB2, a member of the receptor tyrosine kinase family, is frequently over-expressed in breast cancer. Proteolysis of the extracellular domain of ErbB2 results in constitutive activation of ErbB2 ...

The study applied a new approach that installed hairpin internal nuclear localization signal sequences (hiNLS) at selected sites within the backbone of CRISPR-Cas9. This approach contrasts with ...

This signal is known as the nuclear localization signal (NLS) for transport into the nucleus, and the nuclear export sequence (NES) for transport out of the nucleus. "Artificially inducing the ...

(c) The DBD binds to complementary DNA sequences, while the AD recruits transcriptional ... The third component (representing the nuclear localization signal domain) is a nuclear localization signal ...

S sequences of both the viruses were aligned ... or constituted protein motifs such as a nuclear localization signal (NLS) and to study the interactions between SARS-CoV-2 RNA and the S and ...

In this technical session, Creative Biolabs has invited Dr. Leyton to describe the need to develop a more precise method in investigating nuclear transport dynamics of NLS-therapeutics. Moreover, Dr.