Secretory IgA is resistant to degradation and provides passive protection via multiple mechanisms. Breast milk immune factors – mainly sIgA – act either as protective and proactive factors and ...

Formulated to spritz protection into the body via the nose or the mouth—the same portals of entry most accessible to the virus itself—mucosal vaccines could head SARS-CoV-2 off at the pass ...

The programs are based on Leyden Labs’ Mucosal Protection Platform utilizing broadly protective antibodies. Round led by ClavystBio (a life sciences venture investor established by Temasek ...

More information: Victoria Ozberk et al, A Glycolipidated-liposomal peptide vaccine confers long-term mucosal protection against Streptococcus pyogenes via IL-17, macrophages and neutrophils ...

A team of Ohio State researchers engineered a new antibody that could revolutionize influenza prevention through a nasal ...

Bats are known as natural hosts for highly pathogenic viruses such as MERS- and SARS-related coronaviruses, as well as the Marburg and Nipah viruses. In contrast to the severe and often fatal disease ...

However, research into novel adjuvants and intranasal immunity are helping to close this gap to improve mucosal protection. Barriers to Intranasal Immunization One major challenge in targeting the ...

Antibodies in milk are either transferred from plasma by transudation or locally produced by cells that migrate to the mammary gland from other mucosal ... provides passive protection via multiple ...