including a downstream (3′) motif similar to the mooring sequence in apoB mRNA. Bioinformatics analysis based on these features predicted additional APOBEC1 editing targets, which we ...

The minimum protein requirements for editing APOB mRNA are the deaminase enzyme APOBEC1 and the auxiliary factor ACF. Sequence motifs in APOBEC1 and ACF are reminiscent of the domains that are ...