The cast for the main characters will mostly feature professional voice actors, such as Hiroki Yasumoto as Garrett, Koichi Yamadera as Steve, Ayumu Murase as Henry, and Kimiko Saito as Dawn.

The official Japanese voice actor for Varesa in Genshin Impact is Mao Ichimichi. A well-established name in the voice acting industry, Ichimichi has contributed to numerous anime and gaming projects.