Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Selectively inactivating a molecular switch that turns on the gene Nr4a1 in monocytes but not macrophages leads to the loss of patrolling monocytes, which play an important role in suppressing ...

In this application note, explore how scientists can couple a serum-free medium with a xeno-free serum replacement to effectively culture functional monocyte-derived dendritic cells and macrophages.