Nevertheless, such mechanisms appear to play a significant role in the acquisition of resistance to cancer drugs, and while they remain poorly characterized thus far, evidence highlighting their ...

A new case report details a novel genetic mutation linked to drug resistance in a non-small cell lung cancer patient ...

A research team affiliated with UNIST has unveiled an innovative technology to eliminate drug-resistant cancer cells using ...

Understanding the mechanisms of resistance to cancer treatments is necessary to find effective therapies at different stages of the disease. Scientists at UT Southwestern Medical Center studied the ...

Abstract Autophagy is a crucial quality control mechanism that degrades damaged cellular components through lysosomal fusion with autophagosomes ...

A joint research team from the LKS Faculty of Medicine (HKUMed) and the Faculty of Science at the University of Hong Kong has uncovered an unexpected interaction between chemotherapeutic agents and a ...

Danés, principal investigator of the Cancer and Stem Cell Biology Lab at the Champalimaud Foundation, in Lisbon, has shown ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled "Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed.

The relatively new paradigm of 'rationally targeted' cancer drug therapies ... commonly used chemotherapy drugs, establishing specific molecular mechanisms of resistance has been very challenging ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “Acquired RUFY1-RET rearrangement as a ...