Nature5y
78 Differential Role of the Lectin Pathway of Complement Activation in Susceptibility to Neonatal Sepsis
Objective: Newborns are highly susceptible to bacterial sepsis. Mannan-binding lectin (MBL), M-, L- and H-ficolin recognize microorganisms and activate the complement system via MBL-associated ...
Nature1y
The immunological relay race: B cells take antigen by synapse
A number of pathogens can initiate the mannan-binding lectin and alternative pathways of complement activation. The classical and alternative pathways of complement activation all tag antigens ...
Business Insider21d
Omeros' Zaltenibart Gets Rare Pediatric Disease Designation From FDA For C3 Glomerulopathy
Zaltenibart is the most proximal inhibitor of the alternative pathway. It blocks mannan-binding lectin-associated serine protease-3 (MASP-3), the key activator of the alternative pathway ...
Hosted on MSN2mon
Everything you need to know about lectins, and what happens when you eat them
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Hosted on MSN2mon
Study reveals RNA's role in regulating gene expression in cancer cells
By identifying TOP1 as an RNA-binding protein, this research provides new insights into the interplay between RNA and DNA during transcription," says Mannan Bhola, Ph.D., a data analyst in the ...