Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.
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More information: Emilia Bianchini et al, The Role of Hyaluronan/Receptor for Hyaluronan-Mediated Motility Interactions in ...
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Enzyme checkpoint identified in tumor-associated macrophageswe have applied innovative methods of machine learning and artificial intelligence in combination with molecular analyses to discover a new metabolic checkpoint in macrophage polarization.
The study, “Inhibition of glutaminase 1 reduces M1 macrophage polarization to protect against monocrotaline-induced pulmonary ...
In essence, this strategy turns limitations, often considered weaknesses, into strengths. For example, in their 2021 Cell Reports study on macrophage polarization mechanisms, dermatologist Alexander ...
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