The discovery of lysosomes led to many new questions. The most critical question was: what was the physiological function of this "bag" of enzymes? The Function of Lysosomes One of the definitive ...

The Golgi apparatus functions as a molecular assembly line ... they are directed to their appropriate destinations — either lysosomes, storage vesicles, or the plasma membrane (Figure 2).

The humble lysosome, which carries out so many essential functions, appears to live a double life as a potential traitorous agent. "The study highlights the close interaction between lysosomal ...

Damaged lysosomes are repaired by a lipid-based signaling pathway ... who was not involved in the study. But the pathway might function differently in other cells, including neurons, so more work is ...

Understanding how MLRO functions could lead to new therapeutic ... More information: Xiaowen Ma et al, Perspectives of mitochondria-lysosome-related organelle in hepatocyte dedifferentiation ...

Tan suggests that mild cellular stress activating STING could be crucial for maintaining lysosome function and autophagy, ...

2024). The primacy of endolysosomal dysfunction in neurons and microglia aligns with a recent report that, in AD, both ApoE and Aβ aggregate within the microglial lysosome, compromising its function ...