Low-density lipoprotein, known as LDL, is a complex structure with several components that allow cholesterol to circulate in ...

Lepodisiran, a long-duration small interfering RNA targeting lipoprotein(a) synthesis, reduced serum concentrations of ...

Study deciphers the molecular handshake between LDL receptors and apoB100, shedding light on cholesterol metabolism and its role in cardiovascular disease. Study: Structure of apolipoprotein B100 ...

Research has shown a strong association between elevated Lp (a) levels and an increased risk of cardiovascular disease, including heart attacks, strokes, heart failure, blood clots and peripheral ...

Lp(a) is a type of lipid, or fat, in the body that contains and is similar in structure to low-density lipoprotein (LDL) cholesterol, often thought of as "bad cholesterol." Like LDL cholesterol ...

Until now scientists have been unable to visualize the structure of LDL, specifically what happens when it links up with its receptor, a protein known as LDLR. Typically, when LDL binds to LDLR ...

Lipoprotein (a) is a low-density lipoprotein that transports cholesterol in the blood. The lipoprotein (a) test — or Lp(a) test — determines the level of this lipoprotein in the blood, and its ...

Elevated lipoprotein(a) concentrations are associated with atherosclerotic cardiovascular disease. The safety and efficacy of lepodisiran, an extended-duration, small interfering RNA targeting ...