The TCR signals via cytoplasmic tyrosine ... ZAP-70 and CD8 chimeras associated physically and kinase activity was potentiated when Lck and ZAP-70 were expressed together 36.

the CD3 chains are associated with the TCR. Blue: Intracellular receptor phosphorylation: various kinases, such as lymphocyte-specific protein tyrosine kinase (LCK), CSK, and ZAP-70, and phosphatases, ...