Scientists from Singapore and Germany have identified that the proteins lamin A and lamin B receptor are essential for holding silent genes in their correct position at the edge of the nucleus ...

The latest imaging method from the Broad Institute uncovers structural disruptions in the nucleus associated with progeria at ...

It is made up of intermediate V type filaments composed of lamin proteins. It forms an elastic structure near the nuclear periphery and affords a viscoelastic property to the nucleus. At the ...

Each human cell’s nucleus packs about 6 feet of tightly coiled DNA that holds the genetic instructions for every structure and function in the body. To keep the cell working, these threads of DNA must ...

Aging-related inflammation can drive the decline of a critical structural protein called lamin-B1, which contributes to diminished immune function in the thymus, according to research from ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

The accidental rupture of the structure ... army" comprising lamin C, Barrier-to-autointegration factor (BAF), and cytoplasmic cyclic GMP-AMP synthase (cGAS), important proteins with key ...