Huntington’s disease is an inherited neurodegenerative disorder that causes problems with movement, behavior, and cognitive ...

Donated by the family of a young girl with juvenile Huntington's disease, these cells are one of the few patient lines that demonstrate CAG expansion over a reasonable experimental timeframe (in ...

This study identified specific motor skills as highly sensitive markers of juvenile-onset Huntington’s disease (JOHD) progression, offering more precise tools for tracking the disease and ...

Hoffman first reported a juvenile form of HD in 1888 through ... the members of the Huntington's Disease Collaborative Research Group (HDCRG) joined forces and spent the next 10 years working ...

Huntington’s disease (HD) is a progressive ... Symptoms typically appear between the ages of 30 and 50, though juvenile and ...

Mouse studies demonstrated that newly generated neurons connect with brain networks responsible for motor control.

New research shows that the adult brain can generate new neurons that integrate into key motor circuits, findings that may point to a new way to treat neurogenerative disorders.

Brain Changes in Huntington's Disease Decades Before Diagnosis Will Guide Future Prevention Trials Jan. 17, 2025 — Subtle changes in the brain, detectable through advanced imaging, blood and ...

Huntington's disease (HD) is a hereditary neurodegenerative disorder ... About 10 percent of patients have the symptom onset before age 20, which is known as juvenile HD, and about 10 percent have ...