Interleukin-22 (IL-22 ... IL-22 binding protein (IL-22BP) is a soluble inhibitory IL-22 receptor and may represent a crucial regulator of IL-22. We show both in rats and mice that, in the steady ...

Interleukin(IL)-10 and IL-22 are structurally related cytokines ... One possible explanation for the lack of competition for the shared receptor chain might be a lack of direct binding of IL ...

The cytokine profile (including key cytokine receptors as denoted by R), the effector cell type that is activated, and the corresponding types of infections are shown for each Th subgroup.

IL, interleukin. Created with BioRender.com. Credit: DOI: 10.1089/jir.2021.0173 The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in ...

To assess the functional capacity of the interleukin-10 receptor, we stimulated PBMCs from ... through a pathway associated with interleukin-22, interleukin-26, or interferon-λ in ...

Disclosure: Dr. Sebba has received financial support in the form of research grants and lecture honoraria from Hoffmann-La Roche Inc. Cells producing interleukin-6 (IL-6) and the actions of IL-6 ...

Atopic dermatitis (AD) and specific forms of asthma are two medical disorders that are mostly brought on by these inflammations. To fully comprehend the mechanism of therapeutic action and ...

Why measure soluble interleukin-2 receptor levels? Interleukin-2 (IL-2) plays a crucial role as a signaling molecule in the human immune system. It belongs to a group of small, secreted proteins ...

Scientists from Japan have now succeeded in proposing a means to solve this medical conundrum by understanding the role of interleukin-36 receptor antagonists as they act to inhibit the effects of ...

Summary: Tocilizumab is a novel monoclonal antibody that competitively inhibits the binding of interleukin-6 (IL-6) to its receptor (IL-6R). Inhibiting the entire receptor complex prevents IL-6 ...

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection. The receptor can recognize multiple agonists and has been ...