Interleukin-2 (IL-2) and IL-15 have both similar and contrasting functional roles in the life and death of lymphocytes. The heterotrimeric receptors for these cytokines have two subunits in common ...

Cultured CD4 + cells were washed in cold PBS with 2% FCS and 0.1% sodium azide and then stained with fluorescein isothiocyanate (FITC)- or PE-labeled antibody, anti-CD25, anti-CD45RO, anti-CD62L ...

The researchers further tested whether the loss of function experienced by NK cells ... “Crucially, the team also found that treating with Interleukin-15 could re-awaken the dormant killer ...

“The FDA’s decision to grant Fast Track designation for TEV-53408, an investigational anti-IL-15 antibody therapy, reflects the promising nature of the treatment and the urgent unmet need of people ...

Image Credit: Sino Biological Inc. The function of IL-2 is self ... within their receptor subunits, including interleukin-2 (IL-2) IL-4, IL-7, IL-9, IL-15 and IL-21. Amongst members of the γc ...

The Interleukin-1 Receptor-Like 2 (IL-1RL2 ... "It seems that the IL-36IL-1RL2 axis has both inflammatory and healing functions, probably depending on other mediators in the extracellular milieu ...

2008;65(15):1413-1418. Anthony Sebba ... grants and lecture honoraria from Hoffmann-La Roche Inc. Cells producing interleukin-6 (IL-6) and the actions of IL-6 in the body. Ig = immunoglobulin ...

AMSTERDAM--(BUSINESS WIRE)--Calypso Biotech, a leader in the development of Interleukin-15 (IL-15) targeted therapies, announces today completion of dosing of first Celiac Disease patient in the ...

Follow-up continued until a common closing date (November 15, 2008 ... to exert protective effector functions on activation are of little value to the host. Interleukin-2 is known to induce ...