Altogether, these results indicate that blocking IL10 cell surface receptor results in induction of cell cycle arrest and apoptosis through inhibition of IL10-JAK-STAT signaling. These findings ...

The class II cytokine receptors include the receptors for IL10 and the interferons, whereas the class I cytokine receptor family includes the receptors for IL2, IL3, IL4, IL5, IL6, IL7 ...

When a B cell receptor binds to an antigen, that is, to a foreign structure, the B cell is activated and triggers the production of antibodies. Antibodies are essential for our survival and protect us ...

Researchers from the Wellcome Sanger Institute and collaborators have revealed that the interleukin 10 receptor (IL-10R) is critical to prevent uncontrolled whipworm infection in mice and a ...