In order to facilitate IL-4 signaling, IL-4R can additionally complex with the common gamma chain (γc/IL2RG). To support the study of IL-13 Receptors in understanding the immune response to ...

IL-4 and IL-13 are related cytokines which induce both pro- and anti-inflammatory effects depending on the cell type they act upon and the nature of the receptors expressed. The type I receptor ...

These cytokines interact with the IL-4 and IL-13 receptors to start the type 2 inflammatory pathway, which results in Th2 cell differentiation, airway inflammation, and mucus production.

and more so IL-13 represent promising targets. IL-4, which binds to the IL-4Ralpha/gamma receptor complex, is critical for the synthesis of IgE by B-lymphocytes and is also involved in eosinophil ...

Patent covers composition and methods of treating degenerative diseases via administration of IL-4 and IL-13 Empowered Superkines Delivery of selected Bcl-2 family of proteins can prevent cell death, ...