“We were surprised to discover that KMT could work synergistically with the IDH1 mutation to simultaneously target the ... including the Foundation for Metabolic Cancer Therapies, Children with Cancer ...

The medication is a dual inhibitor of the IDH mutation (IDH1 and IDH2 ... better understanding of how genetic mutations ...

Firefighters show higher rates of glioma-linked SBS42 mutational signatures associated with haloalkane exposure, suggesting ...

Tibsovo is already approved in the US as a monotherapy for previously-untreated IDH1-positive AML, as well as for patients with the cancer who have relapsed or are refractory to prior treatment ...

Many cancer types can be identified by certain mutations ... researchers used UR-ddPCR to measure the levels of two genetic mutations, IDH1 R132H and BRAF V600E, which are prevalent in brain ...

Surging interest in cancer bioenergetics has brought drug developers ... They performed metabolic profiling on IDH1 mutant cells and found high levels of a single metabolite, 2-hydroxyglutatarate ...

You would think a brain cancer diagnosis would water down your sense of humour – but this brave young girl is laughing in the ...

Actinium Pharma inks research pact with Memorial Sloan Kettering to support further clinical expansion of Actimab-A's backbone therapy strategy: New York Saturday, March 22, 2025, ...