News-Medical.Net on MSN3d
Firefighting chemicals leave brain cancer-linked mutations, study shows
Firefighters show higher rates of glioma-linked SBS42 mutational signatures associated with haloalkane exposure, suggesting ...
Boston College2d
Could diet help fight brain cancer?
“We were surprised to discover that KMT could work synergistically with the IDH1 mutation to simultaneously target the ... including the Foundation for Metabolic Cancer Therapies, Children with Cancer ...
SurvivorNet on MSN6mon
Breakthrough Hope: A Revolutionary Advance in Treating Brain Cancer Called Glioma– The Drug Vorasidenib Represents The First Progress in 20 Years
The medication is a dual inhibitor of the IDH mutation (IDH1 and IDH2 ... better understanding of how genetic mutations ...
pharmaphorum4y
Servier beefs up in cancer, buying Agios’ oncology business for $1.8bn
with the total value of the deal potentially rising to $2 billion if Agios’ key pipeline candidate vorasidenib – a dual inhibitor of mutated IDH1 and IDH2 in trials for a form of brain cancer ...
Hosted on MSN20d
'Ultra-rapid' testing unlocks cancer genetics in the operating room
Many cancer types can be identified by certain mutations ... researchers used UR-ddPCR to measure the levels of two genetic mutations, IDH1 R132H and BRAF V600E, which are prevalent in brain ...
pharmaphorum2y
FDA clears new first-line use for Servier's Tibsovo in AML
Tibsovo is already approved in the US as a monotherapy for previously-untreated IDH1-positive AML, as well as for patients with the cancer who have relapsed or are refractory to prior treatment ...