Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related death worldwide. Multiple treatment modalities ...

The combination therapy can be used as first-line treatment for unresectable or metastatic forms of the cancer.

More information: Jonggi Choi et al, Statin Use and Risk of Hepatocellular Carcinoma and Liver Fibrosis in Chronic Liver Disease, JAMA Internal Medicine (2025). DOI: 10.1001/jamainternmed.2025. ...

Statin users had a significantly lower 10-year cumulative incidence of hepatocellular carcinoma and hepatic decompensation.

Chronic Hepatitis B (HBV) and Chronic Hepatitis C (HCV) infections are the primary culprits in the progression to liver cirrhosis and hepatocellular ... by scar tissue, a process known as fibrosis.

For example, damage from the hepatitis B or C virus, or long term alcohol drinking above the recommended levels or non alcoholic fatty liver disease. Hepatocellular carcinoma is more likely to develop ...