oral TLR7 agonist RG7854 and HBV core protein allosteric modulator RG7907. Dicerna is retaining an option to co-fund pivotal development of the product globally, which would entitle the company to ...

Researchers update clinical practice guidelines for how to prevent and monitor hepatitis B virus reactivation.

Median HBV DNA at baseline in these eight patients ... Core promoter, precore and core regions. The core protein was found to be mutated in five of the eight patients in their samples analyzed ...

Future Virology. 2008;3(3):253-264. HBV budding is driven by the intrinsic property of the S-protein to form particles at the cytoplasmic side of the ER, even in the absence of mature nucleocapsids.

Chimpanzees have contributed immensely in the development of HBV vaccines ... the results in transgenic lines implicate the HCV core protein in a direct carcinogenic role for the induction ...