to study how and which specific regions of GRB2 and SOS1 bind to each other, especially how they trigger liquid-liquid phase ...

Implementation of the signal information by targeted cells can ... creating a binding site for the SH2 domain of the adapter protein Grb2. The two SH3 domains of Grb2 bind proline rich motifs ...

GRB2 is an adaptor protein that plays a role in cell signal transduction. Here, the authors reveal an attenuation of GRB2 in endometrium from infertile women and show GRB2 knockout in mice results ...