In fact, previous studies have reported that granzyme B (GZMB)-expressing CD8+ T-cells have induce type 1 diabetes by killing pancreatic beta cells. Comparatively, GZMB-expressing KIR+ CD8+ T ...

CHICAGO--(BUSINESS WIRE)--Dr. Michael Rosenblum and his team at MD Anderson Cancer Center, Houston, TX, presented updated data on TGI (Targeted Granzyme B immunotherapy) at the 2018 American ...

A global collaboration agreement has been signed for the development and commercialization of a Granzyme B-targeted Positron Emission Tomography (PET) imaging radiotracer. This radiotracer has the ...

Acute rejection is a serious and frequent complication of renal transplantation, and its diagnosis is contingent on the invasive procedure of allograft biopsy. A noninvasive diagnostic test for ...

This group has generated a number of targeted anticancer therapeutic proteins using granzyme B as the payload and demonstrated potent anti-tumor killing in preclinical studies. The many ...