The common gamma-chain cytokines signal through cytokine receptors that consist of the common cytokine receptor γ chain (γc/CD132/IL2RG). This family includes at least six short-chain cytokines: IL2, ...

In unstimulated cells, the state of G alpha (orange circles) is defined by its interaction with GDP, G beta-gamma (purple circles), and a G-protein-coupled receptor (GPCR; light green loops).

Previous studies have shown that alcohol influences GABAreceptors—a type of receptor in the brain that plays a critical role in the central nervous system by mediating the effects of gamma ...

such as toll-like receptors (TLRs), Fc gamma receptors (FcγRs), and CD40L, which enable them to detect pathogens and participate in innate and adaptive immunity. MKs also phagocytose fungi and ...

The FDA has granted Fast Track designation to ADI-001 for the treatment of refractory systemic lupus erythematosus with extrarenal involvement.

Adicet is advancing a pipeline of "off-the-shelf" gamma delta T cells, engineered with chimeric antigen receptors (CARs), to facilitate durable activity in patients. For more information, please visit ...

ADI-001 is an allogeneic gamma delta chimeric antigen receptor (CAR) T-cell therapy that targets the B-cell antigen, CD20. The investigational immunotherapy is being assessed as a treatment for ...

Adicet is advancing a pipeline of “off-the-shelf” gamma delta T cells, engineered with chimeric antigen receptors (CARs), to facilitate durable activity in patients. For more information ...