GM-CSF (granulocyte-macrophage colony stimulating factor) is a multifunctional cytokine that regulates inflammatory responses, including emergency responses in the bone marrow Mice deficient in GM ...

Overproduction of pro-inflammatory cytokines, such as IL-6, IL-17, TNF-α, IFN-γ, and GM-CSF, has been reported in many clinical and animal experimental studies 13, 15. In addition to the above ...

GM-CSF, a protein that modifies the immune response to the flu, may also help reduce lung inflammation and improve survival during influenza, according to Penn State researchers. E. Scott Halstead ...

In both laboratory models and human clinical samples, the research team pinpointed immune cells called natural killer (NK) cells as an unexpected source of the inflammatory protein GM-CSF in ...

coli, and inflammation of the intestine by diseases such as Crohn's disease. These findings shed light on the apparent benefits of GM-CSF administration to some patients with Crohn's, which have ...

In both laboratory models and human clinical samples, the research team pinpointed immune cells called natural killer (NK) cells as an unexpected source of the inflammatory protein GM-CSF in ...

The protein GM-CSF plays a critical role in maintaining immune tolerance in the gut, with defects in the protein increasing the susceptibility to inflammatory bowel diseases (IBD), according to a ...

GM-CSF is not a new cytokine; we already knew that it can cause or aggravate inflammation. Apart from GM-CSF, however, all the other cytokines studied thus far only played a minor role.

The high levels of GM damage suggest that meningeal B-cell infiltrates may represent the main source of inflammatory/cytotoxic molecules that are released into the CSF to cause cortical tissue ...

They looked for two inflammation markers known as GM-CSF and IL-15, which are cytokines – messenger proteins secreted by cells. Some cytokines have anti inflammatory properties but the two ...

Paucity of appropriate inflammation for cryptococcosis Decreased TNF-α, GM-CSF, interferon-γ, TNF-α, and interleukin-6 in CSF 17,83 Type 1 helper T (Th1) cells that are useful in eliminating ...

GM-CSF is a pathogenic cytokine that causes localized tissue inflammation in MS and other inflammatory autoimmune diseases. Importantly, Satb1 was also found to enhance the expression of the GM ...