Halofuginone can regulate appetite and energy metabolism by increasing the levels of growth differentiation factor 15 (GDF15) ...

Cachexia involves loss of appetite and weight, muscle-wasting ... blocks a hormone known as GDF-15 that regulates appetite and body weight. The patients in the trial had elevated levels of ...

Longing for a civilized and healthy lifestyle, more and more people start to pay attention to weight loss ... increasing the levels of growth differentiation factor 15 (GDF15) and fibroblast ...

Among patients with cancer cachexia and elevated GDF-15 levels, the inhibition of GDF-15 with ponsegromab resulted in increased weight gain and ... severity of appetite loss, nausea, and fatigue ...

The company’s Growth/Differentiation Factor 15 (GDF-15)-targeting monoclonal ... is characterised by weight and muscle mass loss that commonly affects cancer patients, yet there are currently ...

High GDF-15 expression is associated with cancer cachexia including loss of appetite, nausea and weight loss. FL-501 was engineered for higher affinity to GDF-15 and longer plasma half-life ...

Metformin has moderate, if inconsistent, weight loss effects ... Separately, metformin increases levels of growth differentiation factor 15 (GDF-15), which regulates body weight, food intake ...