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Since time immemorial, plants and arbuscular mycorrhizal fungi have coexisted in a mutually beneficial relationship. The ...
Synthetic drug kills fungi but spares kidney cells Another question is why mandimycin does not kill bacteria. Unlike sterols, phospholipids are present in all bacterial plasma membranes (the cell ...
Some existing antifungal drugs like amphotericin B clump together to form large spongelike structures on fungi’s cell membranes, Burke and colleagues previously found. This antifungal sponge ...
Unlike known compounds in this family, mandimycin binds to a novel target in the fungal cell membrane and is therefore ...
a lipid (fat), found in fungi. Ergosterol is similar to but less studied than cholesterol found in animal cells. Lipids form much of the basic structure of cell membranes, which are primarily made ...
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