Disruption of protein interaction in T cells linked to autoimmune disease
Treg function is mainly controlled by a protein called Foxp3 that activates the expression of some genes and represses the ...
Nature26d
Regulatory T-cell development: is Foxp3 the decider?
Four studies examine this question, delving deeply into the role of the transcription factor Foxp3 in governing Treg differentiation and function. Tregs play essential roles in immune homeostasis ...