This implies a failure to form or activate cyclin B1/cdc2 kinase complexes in such cells. These findings reveal an unexpected dependence on FGF receptor signal transduction for prostate cancer cells ...

The FGF-8 protein includes a 22-amino acid (aa) signal sequence, an isoform-specific N-terminal region (30 aa in FGF-8b and 20 aa in FGF-8a, the shortest form), a 125-aa FGF domain, and a 37-aa ...

Activation of FGF receptors can activate multiple signal transduction pathways including the phospholipase C, phosphatidyl inositol 3-kinase, mitogen-activated protein kinase and Stat pathways, all of ...

The first wave channels glucose through the hexosamine biosynthetic pathway (HBP) in epiblast cells, facilitating the ...

such a pacemaker could also function on the FGF cyclic genes and explain the coexistence of a graded signal and an oscillatory response. Other examples of periodic structures generated by an ...