This step occurs by transesterification; in this case, an OH group at the 3′ end of the exon attacks the phosphodiester bond at the 3′ splice site. The adjoining exons are covalently bound ...
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Gene editing tool reduces Alzheimer's plaque precursor in mice"When we originally tried to target this exon with older techniques, it didn't work," said graduate student Shraddha Shirguppe, also a co-first author of the study. "Combining the newer base ...
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