The researchers discovered that this same molecule has a surprising effect on bacteria like E. coli: it disrupts ... Without fimbriae, biofilm formation cannot begin. "Biofilms are like fortresses ...

More information: Jingzhe Guo et al, An evolutionarily conserved metabolite inhibits biofilm formation in Escherichia coli K-12, Nature Communications (2024). DOI: 10.1038/s41467-024-54501-w ...

Biofilm formation is arguably the dominant lifestyle ... in mature biofilms of E. coli K12 using whole-transcriptome analysis (Domka et al., 2007). Prophage genes are among the most highly induced ...

Biofilm formation is astonishingly widespread in nature and appears very early in the fossil record. Biofilm development also occurs in a vastly diverse range of microorganisms, including those ...

Reference: Guo J, Van De Ven WT, Skirycz A, et al. An evolutionarily conserved metabolite inhibits biofilm formation in Escherichia coli K-12. Nat Commun. 2024;15(1):10079. doi: ...

Light and electron microscopy have distinct limitations. Light microscopy makes it difficult to resolve smaller and smaller ...

Light and electron microscopy have distinct limitations. Light microscopy makes it difficult to resolve smaller and smaller features, and electron microscopy resolves small structures, but samples ...

Biofilm doesn’t only smell bad — it could be hazardous, leading to infections of listeria, salmonella, E. coli, MRSA and ...

More than a hundred E. coli cases were linked to contaminated onions produced by Taylor Farms used in McDonald's burgers.

Researchers have now identified a plant metabolite called MEcPP that can disrupt biofilm formation. In plants, this metabolite helps generate critical molecules and is related to biochemical signaling ...