Mutation of Lis1, a key dynein regulator, can lead to the rare mental developmental disorder lissencephaly, or “smooth brain, ...

Dynein is composed of two heavy chains (blue), two intermediate chains (yellow), four light intermediate chains (green) and several light chains, including DYNLRB1 (orange). The Molecular ...

Study: Actl7b deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis. Image Credit: Komsan Loonprom / Shutterstock.com ACTL7B, a testis ...

The stalks of two kinesin heavy chains produce a protein dimer that binds two light chains where most transported ... The role of cytoplasmic dynein includes the transportation of cellular cargo ...