Through rigorous in vitro screening and in vivo validation, they discovered that the secondary bile acid, deoxycholic acid (DCA), produced by C. scindens via the bai operon, effectively suppressed ...

Elevated deoxycholic acid, triacylglycerols, ceramides, and phospholipids were identified in MASH patients, suggesting a noninvasive diagnostic potential. The study used untargeted lipidomic ...